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Table of Contents

World Psychiatric Association Evidence and Experience in Psychiatry Series

Series Editor: Helen Herrman, WPA Secretary for Publications, University of Melbourne, Australia

 

Depressive Disorders, 3e

Edited by Helen Herrman, Mario Maj and Norman Sartorius

ISBN: 9780470987209

 

Substance Abuse Disorders

Edited by Hamid Ghodse, Helen Herrman, Mario Maj and Norman Sartorius

ISBN: 9780470745106

 

Schizophrenia 2e

Edited by Mario Maj, Norman Sartorius

ISBN: 9780470849644

 

Dementia 2e

Edited by Mario Maj, Norman Sartorius

ISBN: 9780470849637

 

Obsessive-Compulsive Disorders 2e

Edited by Mario Maj, Norman Sartorius, Ahmed Okasha, Joseph Zohar

ISBN: 9780470849668

 

Bipolar Disorders

Edited by Mario Maj, Hagop S Akiskal, Juan José López-Ibor, Norman Sartorius

ISBN: 9780471560371

 

Eating Disorders

Edited by Mario Maj, Kathrine Halmi, Juan José López-Ibor, Norman Sartorius

ISBN: 9780470848654

 

Phobias

Edited by Mario Maj, Hagop S Akiskal, Juan José López-Ibor, Ahmed Okasha

ISBN: 9780470858332

 

Personality Disorders

Edited by Mario Maj, Hagop S Akiskal, Juan E Mezzich

ISBN: 9780470090367

 

Somatoform Disorders

Edited by Mario Maj, Hagop S Akiskal, Juan E Mezzich, Ahmed Okasha

ISBN: 9780470016121

Current Science and Clinical Practice Series

Schizophrenia

Edited by Wolfgang Gaebel

ISBN: 9780470710548

 

Obsessive Compulsive Disorder

Edited by Joseph Zohar

ISBN: 9780470711255

Other recent World Psychiatric Association titles

Special Populations

 

The Mental Health of Children and Adolescents: an area of global neglect

Edited by Helmut Remschmidt, Barry Nurcombe, Myron L. Belfer, Norman Sartorius and Ahmed Okasha

ISBN: 9780470512456

 

Contemporary Topics in Women's Mental Health: global perspectives in a changing society

Edited by Prabha S. Chandra, Helen Herrman, Marianne Kastrup, Marta Rondon, Unaiza Niaz, Ahmed Okasha, Jane Fisher

ISBN: 9780470754115

 

Approaches to Practice and Research

 

Religion and Psychiatry: beyond boundaries

Edited by Peter J Verhagen, Herman M van Praag, Juan José López-Ibor, John Cox, Driss Moussaoui

ISBN: 9780470694718

 

Psychiatric Diagnosis: challenges and prospects

Edited by Ihsan M. Salloum and Juan E. Mezzich

ISBN: 9780470725696

 

Recovery in Mental Health: reshaping scientific and clinical responsibilities

By Michaela Amering and Margit Schmolke

ISBN: 9780470997963

 

Handbook of Service User Involvement in Mental Health Research

Edited by Jan Wallcraft, Beate Schrank and Michaela Amering

ISBN: 9780470997956

 

Psychiatrists and Traditional Healers: unwitting partners in global mental health

Edited by Mario Incayawar, Ronald Wintrob and Lise Bouchard,

ISBN: 9780470516836

 

Depression and Comorbidity

 

Depression and Diabetes

Edited by Wayne Katon, Mario Maj and Norman Sartorius

ISBN: 9780470688380

 

Depression and Heart Disease

Edited by Alexander Glassman, Mario Maj and Norman Sartorius

ISBN: 9780470710579

 

Depression and Cancer

Edited by David W. Kissane, Mario Maj and Norman Sartorius

ISBN: 9780470689660

Title Page

Preface

Post-traumatic stress disorder (PTSD) is arguably the most controversial of all the psychiatric diagnoses. There are disagreements about the qualifying events that count as sufficiently traumatic to precipitate PTSD, disagreements about the nature of the typical symptoms that follow exposure to trauma, disagreements about how best to prevent and treat PTSD, and disagreements about what kind of compensation is owed to people with PTSD by society.

At the same time, there have been major advances in our understanding of many aspects of PTSD. The diagnostic classifications of both the World Health Organization (WHO) and the American Psychiatric Association (APA) include the same broad symptom categories (e.g. re-experiencing, avoidance/numbing and arousal) and emphasise that exposure to extremely stressful events can produce profound alterations in cognitions, emotions and behaviour that may persist for decades or a lifetime.

There is also a growing appreciation of the public health burden of PTSD. Trauma continues to be a pervasive aspect of life in the 21st century, in high-, middle- and low-income countries [1]. Furthermore, PTSD and other trauma-related disorders are highly prevalent and disabling, are often associated with other psychiatric and medical disorders, and lead to significant costs for society [2, 3].

We are gradually advancing our scientific understanding of how exposure to traumatic events can produce neurobiological and psychological alterations which, if untreated, may persist indefinitely [4]. Furthermore, although there is not complete consensus across different clinical guidelines [5], there is general agreement that cognitive behaviour therapy and certain medications are the most effective clinical approaches for PTSD.

Many challenges remain. Fundamental information on the psychobiology of PTSD must be translated into effective, evidence-based clinical interventions. The development and testing of additional evidence-based treatments, especially treatments that are culturally sensitive and effective in more traditional ethnocultural settings, is required [6]. A further challenge is to move beyond the traditional clinic to the public health arena, where the focus must shift to resilience, prevention and selective interventions for populations at risk following disasters or mass violence [7].

The World Psychiatric Association (WPA) Evidence & Experience series provides a useful opportunity to work towards an evidence-based and integrative approach to different psychiatric conditions. In this volume, expert clinicians and researchers from around the world rigorously synthesise the data on PTSD, and provide balanced and judicious approaches to the controversies and challenges noted above. The chapters cover many aspects of PTSD, ranging from work on epidemiology and nosology, through research on psychobiology, to work on pharmacotherapy, psychotherapy and community approaches to intervention. Commentaries on each chapter, again from authors around the globe, provide additional depth.

Taken together, this work documents the many advances in empirical work on PTSD, negotiates a middle path through the theoretical controversies and provides clinicians and policy-makers with a practical approach to clinical and community interventions. Given that the field has learned much in recent decades about the kinds of trauma that are typically associated with PTSD, about the natural course of symptoms in response to such traumas, about optimal ways to evaluate and measure such symptoms, and about the best pharmacotherapeutic, psychotherapeutic and community approaches to the prevention and management of PTSD, we believe that this volume is timely. We hope that it will be useful to a broad range of readers.

We thank the many individuals who contributed to this volume, particularly the chapter authors. We also thank Joan Marsh of Wiley-Blackwell, Helen Herrman and Mario Maj of the WPA, and Marianne Kastrup, for their guidance and support; their vision and enthusiasm were pivotal in ensuring the initiation and progress of the volume. We wish to dedicate it to those individuals who have shared their symptoms and histories with us, teaching us the clinical aspects of PTSD and providing inspiring models of courage and resilience in the face of immense adversity.

Dan J. Stein, Carlos Blanco, Matthew J. Friedman

References

1. Green, B.L., Friedman, M.J., de Jong, J. et al. (2003) Trauma Interventions in War and Peace: Prevention, Practice, and Policy, Kluwer Academic/Plenum, Amsterdam.

2. Watson, P.J., Gibson, L. and Ruzek, J.I. (2007) Public health interventions following disasters and mass violence, in Handbook of PTSD: Science and Practice (eds M.J. Friedman, T.M. Keane and P.A. Resick), Guilford Press, New York, pp. 521–539.

3. Blumenfield, M. and Ursano, R.J. (2008) Intervention and Resilience after Mass Trauma, Cambridge University Press, Cambridge, UK.

4. Friedman, M.J., Keane, T.M. and Resick, P.A. (2007) Handbook of PTSD: Science and Practice, Guilford Press, New York.

5. Forbes, D., Creamer, M.C., Bisson, J.I. et al. (2010) A guide to guidelines for the treatment of PTSD and related conditions. Journal of Traumatic Stress, 23, 537–552.

6. Marsella, A.J, Johnson, J.L., Watson, P. and Gryczynski, J. (2008) Ethnocultural Perspectives on Disaster and Trauma: Foundations, Issues and Applications, Springer, New York.

7. Friedman, M.J. (2005). Every crisis is an opportunity. CNS Spectrums, 10, 96–98.

List of Contributors

Dean Ajdukovic

Department of Psychology, University of Zagreb, Zagreb, Croatia

 

David M. Benedek

Department of Psychiatry and Neuroscience; Department of Psychiatry; Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

 

Lucy Berliner

Harborview Center for Sexual Assault & Traumatic Stress, School of Social Work, University of Washington, Seattle, WA, USA

 

Carlos Blanco

Department of Psychiatry, Columbia University, New York, NY, USA

 

Chris R. Brewin

Clinical Educational and Health Psychology, University College London, London, UK

 

Richard A. Bryant

University of New South Wales, Sydney, Australia

 

Abdulrahman M. El-Sayed

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA

 

Matthew J. Friedman

Department of Psychiatry and of Pharmacology & Toxicology, Dartmouth Medical School; National Center for Posttraumatic Stress Disorder, US Department of Veterans Affairs, Hanover, NH, USA

 

Sandro Galea

Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA

 

Asaf Gilboa

The Rotman Research Institute, Baycrest Centre, Toronto, ON, Canada

 

Matthew N. Goldenberg

Department of Psychiatry; Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

 

Derrick Hamaoka

Department of Psychiatry; Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

 

Brian H. Harvey

Division of Pharmacology, Unit for Drug Research and Development, School of Pharmacy, North-West University (Potchefstroom campus), Potchefstroom, South Africa

 

Helen Herrman

Centre for Youth Mental Health, University of Melbourne, Victoria, Australia

 

Jonathan C. Ipser

Department of Psychiatry, University of Cape Town, Cape Town, South Africa

 

Joop de Jong

Department of Psychiatry, VU University Amsterdam, The Netherlands; Boston University, USA; Rhodes University, South Africa

 

Elie G. Karam

Department of Psychiatry and Clinical Psychology; Balamand University Medical School and St Georges Hospital University Medical Center; Institute for Development Research Advocacy and Applied Care (IDRAAC); Medical Institute for Neuropsychological Disorders (MIND), Beirut, Lebanon

 

Marianne Kastrup

Videnscenter for Transkulturel Psykiatri, Psykiatrisk Center København, Strandboulevarden, Denmark

 

Rafael Kichic

Anxiety Clinic, Institute of Cognitive Neurology (INECO) and Institute of Neurosciences, Favaloro University, Buenos Aires, Argentina

 

Channaveerachari Naveen Kumar

Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

 

Karina Lovell

The School of Nursing, Midwifery and Social Work, The University of Manchester, Manchester, UK

 

Suresh Bada Math

Department of Psychiatry, National Institute of Mental Health and Neurosciences (NIMHANS), Bangalore, India

 

Alexander C. McFarlane

Department of Psychiatry, University of Adelaide Node, Centre for Military and Veterans' Health, University of Adelaide, Adelaide, Australia

 

Marcelo F. Mello

Department of Psychiatry, Universidade Federal de São Paulo, São Paulo, Brazil

 

Maria Christine Nirmala

Lead Knowledge Management, Private Multinational Company, Bangalore, India

 

Tarek A. Okasha

Department of Psychiatry, Institute of Psychiatry, Faculty of Medicine, Ain Shams University, Cairo, Egypt

 

Beth Patterson

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

 

Ann M. Rasmusson

Women's Health Sciences Division, National Center for PTSD, VA Boston Healthcare System; Boston University School of Medicine, Boston, MA, USA

 

María L. Reyes-Rabanillo

Psychiatry Service, Veterans Affairs Caribbean Healthcare System, San Juan, Puerto Rico

 

Barbara Olasov Rothbaum

Department of Psychiatry, Trauma and Anxiety Recovery Program, Emory University School of Medicine, Atlanta, GA, USA

 

Arieh Y. Shalev

Department of Psychiatry, Hadassah University Hospital, Jerusalem, Israel

 

Dan J. Stein

Department of Psychiatry, University of Cape Town, Cape Town, South Africa; Mount Sinai School of Medicine, New York, NY, USA

 

Murray B. Stein

Department of Psychiatry and Family and Preventive Medicine, University of California San Diego, CA, USA

 

Robert J. Ursano

Department of Psychiatry and Neuroscience; Department of Psychiatry; Center for the Study of Traumatic Stress, Uniformed Services University of the Health Sciences, Bethesda, MD, USA

 

Michael Van Ameringen

Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada

 

Mildred Vera

Department of Health Services Administration, Medical Sciences Campus, University of Puerto Rico, San Juan, Puerto Rico

 

Eric Vermetten

Military Mental Health, Department of Defence; Department of Psychiatry, University Medical Center, Utrecht, The Netherlands