Table of Contents
Cover
Associate Editors
Title Page
Title Page
Copyright
Dedications
Contributors
Preface to the Fourth Edition
Preface to the First Edition
About the Companion Website
Section I: Approaches to the Patient
Chapter 1: Listening to the Patient
Listening: The Key Skill in Psychiatry
The Primary Tools: Words, Analogies, Metaphors, Similes, and Symbols
How Does One Hear Words in This Way?
Listening as More than Hearing
Common Blocks to Effective Listening
Crucial Attitudes That Enable Effective Listening
Theoretical Perspectives on Listening
Using Oneself in Listening
To Be Found: The Psychological Product of Being Heard
Listening to Oneself to Listen Better
Listening in Special Clinical Situations
Growing and Maturing as a Listener
References
Chapter 2: Physician–Patient Relationship
The Placebo Effect
Roles and Motivations
Modern Medicine and the Physician–Patient Relationship
Attachment Theory and the Physician–Patient Relationship
Formation of the Physician–Patient Relationship
Mental Status of the Patient
Research on the Physician–Patient Relationship
Special Issues in the Physician–Patient Relationship
The Physician–Patient Relationship in Specific Populations of Patients
Conclusion
References
Chapter 3: The Psychiatric Interview: Settings and Techniques
Goals of the Psychiatric Interview
The Psychiatric Database
Conduct of the Interview
References
Chapter 4: The Cultural Context of Clinical Assessment
Introduction: The Cultural Matrix of Psychiatry
What is Culture?
Culture and Gender
The Cultural Formulation
Cultural Competence
Conclusion: The Limits of Culture
References
Chapter 5: Professional Ethics and Boundaries
Introduction
Medical Professionalism
Defining Ethics
Historical Development of the Principles of Medicine
The Doctor–Patient Relationship and Boundaries
Professional Issues for Psychiatrists
Sexual Boundary Violations
Non-Sexual Boundary Transgressions
Conflicts of Interest
Confidentiality
Effects of Information Technology on the Doctor–Patient Relationship
Use of the Internet and Social Media
Teaching Physicians in Professionalism and Ethics
Prevention of Boundary and Other Ethical Violations
Conclusions
Glossary of Terms
References
Chapter 6: Legal Issues in Psychiatric Practice
Introduction
Categories of Legal Issues in Psychiatry
Civil Issues: Patient's Rights
Civil Issues: Doctor–Patient Relationship
Criminal Issues: Competency and Insanity
Other Criminal Issues: Diminished Capacity and Mitigating Factors
Conclusion
References
Section II: A Developmental Perspective on Normal Domains of Mental and Behavioral Functions
Chapter 7: A Psychiatric Perspective on Human Development
Emotional Development
Social Development
Moral Development
High-Risk Periods for Psychopathology
Interlineal Decalage
The Psychiatrist as a Developmentalist
References
Chapter 8: Development of Personality Throughout the Lifecycle
Biological Factors Impacting Personality Development
Psychosocial Factors Impacting Personality Development
Conclusion
References
Chapter 9: Infant Development: The First 3 Years of Life
Theories and Models of Development and the First 3 Years of Life
Lines of Development and Their Discontinuities
Risk and Protective Factors
Illustrative Risk Conditions
Conclusion
References
Chapter 10: Preschool Development
Overview of Development in Preschool Period
Lines of Development
Conclusion
References
Chapter 11: School-Age Development
Conceptual Framework
Biological Development
Cognitive Development
Emotional Development
Sociocultural Development
Moral Development
Risk and Protective Factors
Developmental Psychopathology
References
Chapter 12: Adolescent Development
Historical Perspectives
Conceptual Framework
Biological Development: Puberty
Brain Development
Cognitive Development
Emotional Development
Social Development
Risk Factors, Protective Factors, and Gene–Environment Interactions
Conclusion
Acknowledgment
References
Chapter 13: Adult Development
Towards a Conceptual Framework
Developmental and Cohort Effects
Risk Factors, Protective Factors, and Resilience
Young Adulthood
An Integrated Model for Adult Development
Developmental Formulations of Adulthood
Eriksonian Model of Adult Development
Grief
Transitions and Developmental Crises
The Enduring Importance of Identity Formation
Conclusions: Adult Development – an Ever-Evolving Field
References
Chapter 14: Late Life
Late Life Development
Cognitive Changes
Sensory Changes
Healthy Aging
Physiological Changes
References
Section III: Neuroscientific Foundations of Psychiatry
Chapter 15: Are There Biological Commonalities Among Different Psychiatric Disorders?
Introduction
Diseases of the Mind and Diseases of the Brain
Specific Biological Commonalities Among Disorders
Beyond Gross Anatomical Similarities: Functional Circuitry in Psychiatric Disease
The Ventral Striatum and Mechanisms of Reward
Dysregulation of Reward in Disorders of the Ventral Striatum
The Dorsal Striatum and the Automation of the Routine
Maladaptive Habits in Disorders of the Dorsal Striatum
Prefrontal Cortex: Attention and Behavioral Flexibility
Attentional Deficits in Disorders of the Prefrontal Cortex
Prefrontal Cortex: “Deliberate” Versus “Implicit” Emotion-Regulation Strategies
Dysfunctional Emotion Regulation in Disorders of the Prefrontal Cortex
Research Domain Criteria (RDoC) Project: An Organized Transdiagnostic Research Effort
Conclusion
References
Chapter 16: Genetics of Psychiatric Disorders: Advances in Genetic Epidemiology and Molecular Genetics
Introduction
Genetic Epidemiology
Genetic Epidemiology of Mental Disorders
Advances in the Molecular Genetics of Bipolar Disorder
Recent Advances in the Identification of Genes Underlying Schizophrenia
Use of Endophenotypes for Classification
Collaborative Studies in Genetic Epidemiology
References
Chapter 17: Modeling Psychiatric Disorders in Experimental Animals
Introduction
Defining Phenotypes and Establishing Validity in Animal Models
Dissecting Cognitive and Behavioral Endophenotypes from Complex Mental Disorders
Using Neuropathological or Pharmacological Phenotypes to Test Etiologic and Pathogenic Hypotheses of Psychopathology
A Priori Modeling Genetic, Environmental, and Experiential Etiologies in Psychiatric Disorders
Conclusions
Acknowledgment
References
Chapter 18: The Scientific Basis of Psychotherapy
The Scientific Basis of Psychotherapy
Principles of Psychoanalysis: The Contribution of Freud
Psychoanalysis After Freud
Studies on the Effectiveness of Psychotherapies: Overall Efficacy of Treatment
Conclusions from the literature
Biological and Neuroimaging Studies of Psychotherapy
Conclusion
References
Chapter 19: The Neurobiology of Schizophrenia
Introduction
Neurodevelopmental Concept
Conclusion
Acknowledgment
References
Chapter 20: Neurobiology of Anxiety Disorders
Overview
History and Clinical Picture of Anxiety Disorders
Pathophysiology of Anxiety Disorders
Therapeutic Targets
Genetic Contributions to Anxiety Disorders
Developmental Origins of Anxiety Disorders
Gene–Environment Interactions
Animal Models of Anxiety
Conclusions
References
Chapter 21: Neurobiologic Foundations of Mood Disorders
Nomenclature
Genetics
Pathogenic Mechanisms
Conclusion
Disclosure Statement
References
Chapter 22: Pathophysiology of Addiction
Clinical Picture
Patterns of Substance Use and Substance Use Disorders
Key Components of Vulnerability
Neuropharmacology of Drug Intoxication and Reward
Addiction
Concluding Remarks
References
Chapter 23: Neuroscience of Autism
Introduction
Epidemiology of Autism
Diagnosis and Behavioral Features
Medical and Other Comorbid Features
Developmental and Genetic Mechanisms Implicated in the Etiology of Autism
Neuropathology
Functional Neuroimaging
Behavioral Treatment
Other Treatments
Conclusions
References
Chapter 24: Neurodegeneration and Dementia
Introduction
Alzheimer's Disease
Frontotemporal Dementia
Dementia with Lewy Bodies
Prion Diseases
Conclusions
References
Section IV: Psychological and Social Scientific Foundations of Psychiatry
Chapter 25: Psychiatric Epidemiology
Overview
The Scope of Inquiry in Psychiatric Epidemiology
Epidemiologic Methods
Types of Epidemiologic Studies
Threats to Validity in Epidemiologic Studies
Examples of Psychiatric Epidemiologic Studies
The National Comorbidity Survey Replication (NCS-R)
The World Mental Health Survey Initiative
Future Directions
References
Chapter 26: Cognitive Psychology and Neuroscience
Historical Review of the Cognitive Framework
Overview of Core Cognitive Processes
Conclusions: Modularity and Integration
References
Chapter 27: Social Psychology: Theory, Research, and Mental Health Implications
Introduction
The Genesis of Social Psychology
Attributional Style and Vulnerability to Depression
Summary
Acknowledgments
References
Chapter 28: The Psychodynamic Model of the Mind
Introduction – the Basic Psychodynamic Model
Ego Psychology
Object Relations Theory
Self-Psychology
Attachment Theory
Relational Theory
Concluding Remarks
References
Chapter 29: Cognitive and Behavioral Model of the Mind
Overview of the Cognitive Behavioral Model
Behavioral Theory
Cognitive Theory
CBT Case Conceptualization and Treatment Planning
Application of Cognitive and Behavioral Theories to Other Disorders
Conclusion
References
Chapter 30: Positive Psychology
What is Positive Psychology and Why Is It Necessary?
Theoretical Foundations
Salient Developments in Positive Psychology
New Areas of Investigation
Application of Positive Psychology to Clinical Settings
Future Directions
Conclusion
References
Section V: Manifestations and Assessments of Psychiatric Illness
Chapter 31: Clinical Evaluation and Treatment Planning: A Multimodal Approach
Psychiatric Interview
Physical Examination
Neurological Examination
Psychological and Neuropsychological Testing
Laboratory Assessments
Special Assessment Techniques
Treatment Planning
Conclusion
References
Further Reading
Chapter 32: Consciousness, Orientation, and Memory
Nature of Consciousness
Levels of Consciousness
Qualitative Changes in Consciousness
Memory
Intelligence
Clinical Evaluation
Conclusion
References
Chapter 33: Alterations of Speech, Thought, Perception, and Self-Experience
Disorders of Speech
Disorders of Thought
Perceptual Disturbances
Disorders of Identity and Will
Conclusion
References
Chapter 34: Emotions
Behavioral, Neurological, and Cognitive Components of Emotion
Assessment of Mood and Affect in the Clinical Interview
Emotional Expression of Personality Disorders
Emotional Expression of Anxiety
Emotional Expression of Depression
Emotional Expression of Euphoria
Emotional Expression of Fear
Emotional Expression of Apathy
Emotional Expression of Hostility, Anger, and Rage
Disturbances of Affect Incongruent with Mood
Conclusion
References
Chapter 35: Behavior and Adaptive Functioning
Personality Style
Domains of Functioning
Assessing Behavior and Adaptive Functioning in the Clinical Interview
Problematic Patterns of Behavior
Conclusion
References
Chapter 36: Physical Signs and Symptoms
Evaluation of Physical Signs and Symptoms
Physical Manifestations of Anxiety
Physical Manifestations of Mood Disorders
Physical Disorders Causing Secondary Mental Symptoms
Intoxication and Withdrawal
Agitation
Physical Symptoms Without Known Etiology
Factitious Symptoms
Conclusion
References
Chapter 37: Neuropsychological Assessment and Neurophysiological Evaluation
Introduction
Neuropsychological Assessment
Neurophysiological Assessment
Summary
References
Chapter 38: Brain Imaging in Psychiatry
Introduction
Structural Imaging Modalities
Functional Imaging Modalities
In Vivo
Neurochemical Research: Molecular Imaging
Other Imaging Technologies
Clinical Use of Imaging in Psychiatric Populations
Summary
References
Chapter 39: The Initial Psychiatric Evaluation of Children and Adolescents
Elements of the Psychiatric Evaluation
Psychological Evaluation
Laboratory Assessment
Outcome of the Evaluation
Conclusion
References
Chapter 40: Culture and Psychiatric Diagnostic Systems
Introduction
Presence of Culture in DSM and ICD Classifications
Cultural Considerations for the Assessment of Major Forms of Psychopathology
The Case of Culture-Bound Syndromes or Cultural Concepts of Distress
Person-centered Integrative Diagnosis (PID)
Conclusions
Acknowledgement
References
Section VI: Disorders
Chapter 41: Psychiatric Classification
Introduction
Goals of a Classification System
Approaches to Classification
Historical Background
DSM–5 Classification and Diagnostic Codes
The Future of Psychiatric Classification
References
Chapter 42: Neurodevelopmental Disorders: Intellectual Disability
Treatment
Diagnosis of Co-occurring Mental Disorders
Treatment of Mental Disorders in ID/IDD
Summary
Acknowledgments
References
Chapter 43: Neurodevelopmental Disorders: Communication Disorders
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
References
Chapter 44: Autism Spectrum Disorder
Historical Context
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
References
Chapter 45: Neurodevelopmental Disorders: Attention-Deficit/Hyperactivity Disorder
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
References
Chapter 46: Neurodevelopmental Disorders: Learning Disorders
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
Acknowledgments
References
Chapter 47: Neurodevelopmental Disorders: Motor Disorders
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
References
Chapter 48: Schizophrenia and Other Psychoses
Historical Overview
Diagnosis
Etiology
Pathophysiology
Clinical Manifestations and Phenomenology
Treatment
Diagnosis
Etiology
Treatment
Diagnosis
Etiology
Treatment
Diagnosis
Etiology
Treatment
History
Diagnosis
Etiology
Treatment
Diagnosis
Etiology
Treatment
Comparison of DSM-5/ICD-10 Diagnostic Definitions
References
Chapter 49: Bipolar (Manic Depressive) Disorders
Introduction
Diagnosis
Phenomenology
Additional Features: Psychosis and Rapid Cycling
Screening for Manic Depressive Disorder
Etiology and Pathophysiology
Treatment
References
Chapter 50: Depressive Disorders: Major Depressive Disorder and Persistent Depressive Disorder
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
References
Chapter 51: Depressive Disorders: Premenstrual Dysphoric Disorder
Diagnosis
Etiology and Pathophysiology
Treatment
Conclusion
Comparison of DSM-5/ICD-10 Diagnostic Criteria
References
Chapter 52: Childhood Mood Disorders: Major Depressive Disorder, Bipolar Disorder, and Disruptive Mood Dysregulation Disorder
Introduction
Historical Overview and Controversy
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
Acknowledgments
References
Chapter 53: Anxiety Disorder in Youth: Separation Anxiety, Social Anxiety, and Generalized Anxiety Disorders
Introduction
Diagnosis
Diagnosis
Diagnosis
Etiology
Treatment
Summary
References
Chapter 54: Anxiety Disorders: Social Anxiety Disorder and Specific Phobia
Introduction
Diagnosis
Treatment
Comparison of DSM-5/ICD-10 Diagnostic Criteria
References
Chapter 55: Anxiety Disorders: Panic Disorder and Agoraphobia
Introduction
Panic Attacks
Diagnosis
Diagnosis
Etiology and Pathophysiology
Treatment
Comparison of DSM-5 and International Classification of Diseases, Tenth Revision (ICD-10) Diagnostic Criteria
References
Chapter 56: Anxiety Disorders: Generalized Anxiety Disorder
Diagnosis
Assessment Issues
Etiology and Pathophysiology
Treatment
References
Obsessive–Compulsive and Related Disorders: Introduction
References
Chapter 57: Obsessive–Compulsive and Related Disorders: Obsessive–Compulsive Disorder and Hoarding Disorder
Obsessive–Compulsive Disorder and DSM-5
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Conclusion
Acknowledgments
References
Chapter 58: Obsessive–Compulsive and Related Disorders: Body Dysmorphic Disorder, Trichotillomania (Hair-Pulling Disorder), and Excoriation (Skin-Picking) Disorder
Diagnostic Features
Etiology and Pathophysiology
Treatment
Diagnostic Features
Etiology and Pathophysiology
Treatment
Diagnostic Features
Etiology and Pathophysiology
Treatment
References
Chapter 59: Trauma- and Stressor-Related Disorders: Posttraumatic Stress Disorder, Acute Stress Disorder, and Adjustment Disorder
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Treatment
References
Chapter 60: Trauma- and Stressor-Related Disorders: Reactive Attachment Disorder and Disinhibited Social Engagement Disorder
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
References
Chapter 61: Dissociative Disorders
Introduction
Development of the Concept
Epidemiology
Theoretical and Research Issues: Models and Mechanisms of Dissociation
Dissociative Disorders: Diagnosis and Treatment
Diagnosis
Treatment
Diagnosis
Treatment
Diagnosis
Treatment
Diagnosis
Treatment
Dissociative Trance
Possession Trance
Cultural Context
Treatment
Acute Dissociative Reactions To Stressful Events
Dissociative Disorders Treatment Outcome Studies
Comparison of DSM-5 and ICD-10 Diagnostic Criteria
Conclusion
References
Chapter 62: Somatic Symptom and Related Disorders: Somatic Symptom Disorder, Illness Anxiety Disorder, and Conversion Disorder
Introduction
Definition and Diagnostic Features
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Definition and Diagnostic Features
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Definition and Diagnostic Features
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Definition and Diagnostic Features
Conclusion
References
Chapter 63: Somatic Symptom and Related Disorders: Factitious Disorders
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
References
Chapter 64: Feeding and Eating Disorders
Introduction
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Definition and Diagnostic Features
Etiology and Pathophysiology
Treatment
Definition and Diagnostic Features
Definition and Diagnostic Features
References
Chapter 65: Childhood Elimination Disorders
Definition
Course and Natural History
Diagnosis and Differential Diagnosis
Etiology and Pathophysiology
Treatment
Assessment and Management of Diurnal Enuresis
Definition
Course and Natural History
Diagnosis and Differential Diagnosis
Treatment
References
Chapter 66: Sleep and Sleep–Wake Disorders
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Diagnostic Features
Associated Features
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
References
Section VI: Disorders (continued)
Chapter 67: Sexual Dysfunctions
Introduction
Diagnostic Commonalities Across Dysfunctions
Etiological Commonalities Across Dysfunctions
Psychosocial Assessment Across Dysfunctions
Treatment Commonalities Across Dysfunctions
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Treatment
Conclusion
References
Chapter 68: Gender Dysphoria
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
References
Chapter 69: ODD and Conduct Disorder
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Summary
References
Chapter 70: Disruptive, Impulse-Control, and Conduct Disorders: Intermittent Explosive Disorder, Kleptomania, and Pyromania
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Comparison of DSM-5 and ICD-10 Diagnostic Criteria
References
Chapter 71: General Approaches to Substance Use Disorders
Definitions
Diagnosis and Assessment
Standard Treatments
Comparison of DSM-5 and WHO's ICD-10 Definitions
References
Further Reading
Chapter 72: Substance-Related Disorders: Alcohol-Related Disorders
Introduction
Patterns of Drinking and Burden of Disease
Alcohol Use Disorder
Etiology and Pathophysiology
Alcohol-Induced Disorders
Assessment of Alcohol Use Disorder and Other Alcohol-Related Disorders
Prevalence and Comorbidity
Natural History
Treatment
Conclusion
Acknowledgments
References
Chapter 73: Substance Use and Addictive Disorders: Caffeine
Introduction
Caffeine Intoxication
Caffeine Withdrawal
Caffeine Use Disorder
Caffeine-Induced Anxiety Disorder
Caffeine-Induced Sleep Disorder
Conclusion
Acknowledgment
Comparison of DSM-5 and WHO's ICD-10 Definitions
References
Chapter 74: Substance Abuse: Cannabis-Related Disorders
Introduction
Epidemiology of Cannabis Abuse and Dependence
Endocannabinoid System
Synthetic Cannabinoids
Treatment of Cannabis-Related Disorders
Pharmacotherapy in Cannabis Self-Administration or Intoxication
Conclusion
Comparison of DSM-5 and WHO's ICD-10 Definitions
References
Chapter 75: Substance Abuse: Phencyclidine Use Disorders
Phencylidine: DSM-5 Cross-Reference
Phencyclidine Intoxication
Epidemiology
Diagnosis and Differential Diagnosis
Assessment
Relevant Physical Examination and Laboratory Findings
Differential Diagnosis
Standard Approach to Treatment
Special Features Influencing Treatment
Conclusion
Comparison of DSM-5 and WHO's ICD-10 Definitions
References
Chapter 76: Substance Abuse: Hallucinogen- and MDMA-Related Disorders
Introduction
Ethnobotanical Hallucinogens
Synthetic Hallucinogens
Human Experimentation with Hallucinogens
MDMA (“Ecstasy”)
Hallucinogen Intoxication
Hallucinogen Abuse
LSD-Related Psychotic Disorders
Hallucinogen Persisting Perception Disorder (HPPD)
MDMA
References
Chapter 77: Substance Abuse: Inhalant-Related Disorders
Introduction
Substances Inhaled
Inhalant Use Disorder
Inhalant-Induced Disorders
Psychiatric Disturbances Associated with Organic Solvent Abuse
Toxicology of Inhalant Abuse
Clinical Manifestations after Chronic Inhalant Abuse
Issues in the Clinician–Patient Relationship
Conclusion
References
Chapter 78: Substance Abuse: Opioid-Related Disorders
Introduction
Opioid-Related Disorders – DSM-5 Definitions and Clinical Features
Treatment
Harm Reduction
The Affordable Care Act (ACA) and Substance Use Disorders
Issues in the Clinician–Patient Relationship
Conclusion
References
Chapter 79: Substance Abuse: Sedative–Hypnotic or Anxiolytic Use Disorders
Introduction
Benzodiazepine Receptors
Sedative–Hypnotics as Street Drugs
Iatrogenic Sedative–Hypnotic Dependence
Primary Drugs of Abuse
Sedative, Hypnotic, or Anxiolytic Intoxication
Sedative, Hypnotic, or Anxiolytic Use Disorder
Treatment
References
Chapter 80: Stimulant Use Disorders
Introduction
Background
Epidemiology
Etiology and Pathophysiology
Course and Natural History of Stimulant Use Disorders
Diagnosis of Stimulant Use Disorders
Medical Complications of Stimulant Abuse
Treatment of Stimulant Use Disorders
Special Topics
Conclusion
Comparison of DSM-5 and WHO's ICD-10 Definitions
Acknowledgments
References
Chapter 81: Substance-Related and Addictive Disorders: Tobacco-Related Disorders
Diagnosis
Definition and Diagnostic Features
Assessment
Epidemiology
Comorbidity Patterns
Course
Differential Diagnosis
Tobacco Use Differences by Gender and Ethnicity
Etiology and Pathophysiology
Treatment
Problems in Management
Special Considerations in Treatment
References
Chapter 82: Gambling Disorder
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
Comparison of DSM-5 and WHO's ICD-10 Definitions
References
Chapter 83: Neurocognitive Disorders
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnostic Features
Etiology and Pathophysiology
Diagnostic Features
Etiology and Pathophysiology
Diagnostic Features
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnostic Features
Etiology and Pathophysiology
Diagnostic Features
Etiology and Pathophysiology
Diagnostic Features
Etiology and Pathophysiology
Diagnostic Features
Etiology and Pathophysiology
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
References
Chapter 84: Personality Disorders
Introduction
Definition
Diagnosis
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Definition
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Diagnosis
Etiology and Pathophysiology
Treatment
Definition
Diagnosis
Epidemiology and Comorbidity
Etiology and Pathophysiology
Treatment
Acknowledgments
References
Chapter 85: Paraphilic Disorders
Introduction
Diagnosis
Etiology and Pathophysiology
Treatment
References
Chapter 86: Relational Problems
Introduction
Definition
Problems Related to Family Upbringing
Other Problems Related to Primary Support Group
Constructs and Manifestations of Relational Problems
Diagnosis of Relational Disorders
Treatment
Case Example
Conclusion
References
Section VII: Psychotherapeutic and Psychosocial Treatments
Chapter 87: Organization and Economics of Mental Health Treatment
Introduction
Expenditures on Mental Health and Substance Abuse
Utilization of Mental Health Services
Financing Mechanisms
New Models of Integrated Care
Private Practice
Conclusion
References
Chapter 88: Individual Psychoanalytic Psychotherapy
What Is Psychotherapy?
Expressive–Supportive Continuum
Theory of Psychoanalytic Psychotherapy
How Does Psychoanalytic Psychotherapy Work?
How Does Psychoanalytic Psychotherapy Differ from Psychoanalysis?
Tasks of the Psychoanalytic Psychotherapist
Indications for Psychoanalytic Psychotherapy
Contraindications to Psychoanalytic Psychotherapy
Supportive Psychoanalytic Psychotherapy
Ethnocultural Issues in Psychotherapy
Is Psychoanalytic Psychotherapy Effective?
Long-Term Versus Brief Psychotherapies
Disconnection Between Psychotherapy Practice and Research
Towards a Neurobiology of Psychotherapy
Conclusion
References
Chapter 89: Brief Psychotherapies
A Short History of Brief Therapy
Brief Therapies: Availability, Effectiveness, and Cost-Effectiveness
Efficacy of Brief Psychodynamic Therapy: the Evidence
Models of Brief Psychotherapy
Factors Common to the Brief Therapies
Conclusion
References
Chapter 90: Cognitive and Behavioral Therapies
Cognitive Model
Behavioral Model
Cognitive and Behavioral Treatment Strategies
Behavioral Techniques
Formulation of Treatment
Conclusion
Acknowledgments
References
Chapter 91: Interpersonal Psychotherapy*
Introduction
Background
Conducting IPT
Research Findings: IPT for Mood Disorders
IPT for Non-Mood Disorders
Training
The Future
References
Chapter 92: Supportive Psychotherapy
The Evolution of Supportive Psychotherapy
Theoretical Approach of Supportive Psychotherapy
Indications for Supportive Psychotherapy
Supportive Psychotherapeutic Strategies
Assessment and Case Formulation
The Goals of Supportive Psychotherapy
Interventions of Supportive Psychotherapy
The Therapeutic Relationship
Efficacy of Supportive Psychotherapy
Conclusion
References
Chapter 93: Motivational Interviewing
Introduction
What is Motivational Interviewing?
What Isn't Motivational Interviewing?
Processes and Practices
Other Applications
Learning Motivational Interviewing
Dissemination of Motivational Interviewing
Future Research Directions
Conclusion
Acknowledgments
References
Chapter 94: Hypnosis
Introduction
Historical Background
Definition and Components
Myth Dispelled: What Hypnosis Is and What It Is Not
Hypnotizability Scales
Hypnotizability and Psychiatric Disorders
Applications of Hypnosis
Neurophysiological Correlates of Hypnosis
Enhancing Hypnotizability
Conclusion
References
Chapter 95: Group Psychotherapy
History of Group Therapy
Therapeutic Factors
Comparison of Types of Groups
Beginning and Maintaining Groups
Pregroup Preparation
Group Development
Group Process
Therapist Interventions
Concurrent Therapies
Research
Training
Future Directions
References
Chapter 96: Family and Couple Therapy
Introduction
Different Levels for Couple and Family Interventions
Specific Approaches to Couple and Family Therapy
Family-Centered Mental Health Services in Global Mental Health
Conclusion
References
Chapter 97: Partnerships for Meaningful Community Living: Rehabilitation and Recovery-Informed Practices
Introduction
Interventions
Conclusion
References
Chapter 98: Advocacy, Self-Help, and Client-Operated Services
Introduction
Advocacy
Peer/Family Support Models
Client-Operated Services
Conclusion
References
Chapter 99: Early Intervention for Better Mental Health Services
Introduction
EI for Young People with Psychosis and At Risk Mental States
Cost-Effectiveness of Early Intervention in Psychosis
Worldwide Dissemination
Prevention, Management of Sub-threshold states, Early Intervention, the Critical Period, and Clinical Staging
Myths and Realities in Early Intervention
The Definition of, and Rationale for, Early Intervention Across the Disorder, Stage of Life, Setting and Phase of Care Spectra
Is Early Intervention Really a New Idea?
Should Access to Early Intervention Teams Be Diagnosis- and/or Time-Limited
Are Early Prevention and Intervention Just for Young People With First-Episode Psychosis?
What are the Essential Ingredients of an Early Intervention Approach? Underlying Principles of Early Intervention Provision
Service Quality: Defining a Good Service
Ripple Effects of Early Intervention Teams
Can There Be Early Prevention and Intervention of Chronicity?
Can We Do Early Intervention of Well-Being and Wellness, Including Physical Wellness?
The Overall Benefits of an Early Intervention Approach
Conclusion
Acknowledgments
References
Chapter 100: Telemedicine, Smart Devices, Social Media, and the Human/Technology Interface
Introduction
Telemedicine and Telepsychiatry
The Mobile Revolution: from Bigger and Better to Ubiquitous and a Continuum of Platforms
The Internet Environment - e-Health
Social Media
Virtual Reality
Interactive Video Games and Virtual Worlds
The Human/Technology Interface
What Lies Ahead?
Conclusion
References
Section VIII: Pharmacological and Brain Stimulation Treatments
Chapter 101: General Principles of Pharmacologic Therapy
Introduction
Pharmacokinetics
Pharmacodynamics
Safety and Efficacy
Summary
Acknowledgment
References
Chapter 102: Psychopharmacology: Ethnic and Cultural Perspectives
Dispelling the “Color-Blind” Approach
The Cultural Context of Psychopharmacotherapy
Clinicians' Attitudes
Adherence
Expectation (“Placebo”) Effects
The Concomitant Use of Alternative/Indigenous Treatment and Healing Methods
Biological Diversity and Its Consequence in Psychotropic Responses
Genetic Polymorphism of Genes Encoding “Drug-Metabolizing Enzymes”
Factors Affecting the Expression of Drug-Metabolizing Enzymes
Genetic Polymorphism of Genes Encoding Receptors, Transporters, or Other Therapeutic Targets
Genetic Polymorphism of Other Genes Affecting Pharmacological Responses
Summary and Future Research Directions
References
Chapter 103: Antidepressants
Theoretical Basis for Treatment
The Basis for Determining Efficacy
The Development of New Antidepressants
The Formulation of Treatment
Initiation of Treatment
Phases of Treatment
Recommendations for the Use of Antidepressants
Future Pharmacotherapies
References
Chapter 104: Antipsychotic Drugs
Introduction
History of Antipsychotic Drug Development
Mechanism of Action of Antipsychotic Agents
Use of Plasma Levels of Antipsychotic Drugs
Drug Interactions and Antipsychotic Agents
Antipsychotic Medications and Pregnancy
Adverse Effects
Future Directions in Antipsychotic Drug Research and Treatment
Conclusions
Conflict of Interest Statements
References
Chapter 105: Mood Stabilizers
Introduction
Defining Mood Stabilizers
Mood Stabilizers for Acute Mania
Mood Stabilizers for Acute Bipolar Depression
Mood Stabilizers for Maintenance Treatment of Bipolar Disorder
Mood Stabilizers for Rapid Cycling Bipolar Disorder
Redefining Mood Stabilizers
Conclusion
References
Chapter 106: Anxiolytic Drugs
Introduction
A General Approach to Using Medication with Anxious Patients
Generalized Anxiety Disorder
Social Anxiety Disorder
Panic Disorder
Posttraumatic Stress Disorder
Obsessive–Compulsive Disorder
Future Directions
Conclusion
References
Chapter 107: Pharmacologic Treatment of Insomnia
Introduction
Sleep–Wake Cycle Regulation
Historical Overview
FDA-Approved Insomnia Treatment Medications
Prescription Medication Off-Label Use
OTC Medications
Complementary and Alternative Substances
Agents in Development
Insomnia in Psychiatric Patients
Conclusion
References
Chapter 108: Stimulants
Medications
Pharmacology
Indications and a Review of Efficacy Data in Children
Side Effects
Clinical Use
Acknowledgment
Acute Effects
Chronic Effects
Studies in Medically Ill and Geriatric Patients
Stimulants in Late-Life Depression
Stimulant Augmentation in Depression
Acceleration of Response with Stimulants
Dextroamphetamine Versus Methylphenidate
Side Effects and Safety
Abuse Potential
Modafinil for Depression
Conclusion
References
Further Reading
Chapter 109: Cognitive Enhancers and Treatments for Alzheimer's Disease
History and Background
Regulatory and Methodological Issues
Etiopathology and Implications for Treatment
Treatment Paradigms
Summary
Acknowledgment
References
Chapter 110: Integrative and Complementary Medicine in Psychiatry
Introduction
Mood Disorders
Anxiety Disorders
Schizophrenia and Other Psychotic Disorders
Insomnia
Cognitive Enhancement
Attention-Deficit/Hyperactivity Disorder (ADHD)
Herb–Drug Interactions
The Importance of the Doctor–Patient Relationship
Summary
Acknowledgments
References
Chapter 111: Brain Stimulation in Psychiatry
Introduction
Brain Stimulation: a Unique Family of Neuromodulation Interventions
Applications of Brain Stimulation in Psychiatry
Brain Stimulation Tools in Psychiatry
Conclusions and Future Directions
Acknowledgments
References
Chapter 112: Pharmacological Management of Treatment-Resistant Unipolar Depression
Introduction
Evaluation of the Patient
Medication Management
Switching Antidepressants
Augmentation
Combination Antidepressant Strategies
Novel Agents
Proposed Algorithm for Treatment
General Principles of Management
Indications for Psychotherapy Combination Treatment
Indications for Brain Stimulation Treatment
Limitations of Current and Likely Research
Acknowledgment
References
Chapter 113: Pharmacological Treatment of Substance Abuse Disorders
Pharmacological Mechanisms of Treatment for Substance Use Disorders
Alcohol
Opiates
Nicotine Dependence
Stimulants: Cocaine and Amphetamines
Marijuana and Cannabinoids
Summary
Acknowledgments
References
Chapter 114: Antidepressant Use in Perinatal Depression
Introduction
Epidemiology of Antidepressant Use and Depressive Episodes in Pregnancy
Spontaneous Abortion
Fetal Death
Gestational Age and Preterm Birth
Fetal Growth
Congenital Malformations
Neonatal and Post-Neonatal Demise
Neonatal Behavioral Syndrome
Persistent Pulmonary Hypertension
Neurodevelopmental Effects
Summary
Acknowledgments and Disclosure Statement
References
Chapter 115: Adherence to Medication in Psychiatric Disorders
Introduction
Shared Decision-Making
Theoretical Models of Health Behavior
Prevalence of Poor Adherence to Medication
Patterns of Medication Noncompliance
Measurement of Medication Compliance
Indirect Measures
Risk Factors for Noncompliance
Specific Patient Populations
Intervention Strategies
Conclusions
Acknowledgment
References
Section IX: Psychosomatic Medicine and Collaborative Care
Chapter 116: Psychosomatic Medicine and Psychological Factors Affecting Other Medical Conditions
Introduction
History
International Developments in Psychosomatic Medicine
Psychosomatic Medicine as a Scholarly Discipline
The Clinical Practice of Psychosomatic Medicine
Psychiatric Diagnosis in the Medically Ill
Psychological Factors Affecting Other Medical Conditions (PFAOMC)
Psychological Factors in Specific Medical Disorders
Clinical Vignettes
References
Chapter 117: Child and Adolescent Psychiatric Consultation
Introduction
Principles of Consultation
Conclusion
References
Chapter 118: Psychiatric Conditions During Peripartum and Perimenopause
Pregnancy
Postpartum Psychiatric Illness
Perimenopause
Conclusion
References
Chapter 119: Management of the Patient in Geriatric Psychiatry
Introduction
Approach to the Patient
Management of Dementia
Management of Behavioral Disturbance in Dementia
Etiology of Behavioral Disturbance
Management of Depression in the Elderly
Conclusion
References
Chapter 120: Death and Bereavement
Introduction
Death and Dying
Bereavement and Grief
Acknowledgment
References
Chapter 121: Integrated/Collaborative Models of Care
Introduction
Models of Integrated Care
Evidence Base for Collaborative Care
Core Principles of Collaborative Care
The Collaborative Care Team
Psychiatric Consultation in Collaborative Care
The Consulting Psychiatrist as Educator
Implementing Effective Collaborative Care Programs
Example Programs
Conclusion
References
Section X: Emergency Psychiatry and Violence
Chapter 122: Modern Psychiatric Emergency Care
Introduction
History
Models of Care
Goals for Care
Future Endeavors
Conclusion
References
Chapter 123: Management of Agitation
Violent Sequelae of Severe Agitation
Agitation Measurement Scales
Decreasing Use of Restraints
A Change in Attitude, Culture, and Environment
Modern Guidelines
Initial Management of the Agitated Patient
Evaluating the Agitated Patient
De-escalation
Psychopharmacology of Agitation
The Use of Oral Antipsychotics
Proper Use of Seclusion and Restraint
Summary
References
Chapter 124: Restraint and Seclusion
Controversies Regarding Restraint and Seclusion
State of Research
The Legal Rights of Psychiatric Patients
The State of Education
Conclusion
References
Chapter 125: Management of the Suicidal Patient
Introduction
What Is Suicidal Ideation and Behavior?
Scope of the Problem of Suicidal Behavior: Mortality and Morbidity
Risk and Protective Factors
Demographic Risk and Protective Factors
Clinical Risk and Protective Factors
Management of the Suicidal Patient
Treatment
Legal and Ethical Issues
Conclusion
References
Chapter 126: Treatment of Aggressive and Violent Behavior
Introduction and Background
Violence and Mental Illness
Violence, Physiology, and Biology
Treatment of Aggression
Conclusion
References
Chapter 127: Managing Psychological Consequences in Disaster Populations
Disaster Psychiatry
Conclusion
References
Chapter 128: Psychiatric Management of Victims of Intimate Partner and Sexual Violence
Introduction
Epidemiology
Acute Management of IPV and SV
Long-Term Mental Health Sequelae of IPV and SV
Long-Term Management Considerations
Conclusion
References
Chapter 129: Rehabilitating Survivors of Torture
Introduction
Medical Aspects of Torture
Identifying Consequences of Torture and Need for Treatment
General Therapeutic Considerations
Treatment Interventions
Outcome Evaluation
Organization of Care: Rehabilitation Models
Specific Populations and Issues
Conclusion
Acknowledgment
References
Chapter 130: Correctional Psychiatry
Epidemiology of Mental Illness in Correctional 1 Populations
Criminal Justice/Mental Health Collaborative Interventions
Legal Considerations
Mental Health Care in the Correctional Setting
Special Topics and Challenges in the Correctional Setting
Conclusion
Disclosure
References
Section X: Emergency Psychiatry and Violence
Chapter 131: Research Methodology and Statistics
Introduction
Issues of Design
Designs and Threats to Validity
Power and Statistical Inference
Issues of Measurement
Standard Statistical Techniques
Basic Statistical Parameters
Univariate Approaches
Multivariate Approaches
Conclusion
References
Chapter 132: A Brief History of Psychiatry
Ancient Times
Beginnings of a Methodological Approach to Mental Phenomena
Roman, Greek, and Other Influences in Early Christian Times
Post-Roman and Medieval Times
16th Century: The Beginnings of Modern Psychiatry
17th Century: Slow Progress in Description and Empiricism
18th Century
19th Century
20th Century
New Developments
Conclusion
References
Primary Sources
Secondary Sources
Index
End User License Agreement
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